Andrographis paniculata Ethanol Extract Alleviates High Glucose-induced Senescence of Human Umbilical Vein Endothelial Cells via the Regulation of mTOR and SIRT1 Pathways

BACKGROUND: Chronic exposure of high glucose (HG) in endothelial cell induces senescence which may contribute to the development and progression of age-related diseases including insulin resistance. Andrographis paniculata improves insulin resistance in recent in vitro and in vivo studies. Anti-infl...

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Bibliographic Details
Published in:Indonesian Biomedical Journal
Main Authors: Nurul Gusti Khatimah, Wawaimuli Arozal, Agian Jeffilano Barinda, Radiana Dhewayani Antarianto, Novi Silvia Hardiany, Ippei Shimizu, Muhamad Rizqy Fadhillah
Format: Article
Language:English
Published: Secretariat of The Indonesian Biomedical Journal 2024-08-01
Online Access:https://inabj.org/index.php/ibj/article/view/3067