Ranpirnase (OKG-0301), a Novel Ribonuclease, Demonstrates Antiviral Activity against Adenovirus in the Ad5/NZW Rabbit Ocular Replication Model

Adenovirus ocular infections are common ocular viral infections seen worldwide, for which there is no approved antiviral therapy available. Ranpirnase is a novel ribonuclease which preferentially degrades tRNA resulting in an inhibition of protein synthesis. The study goal was to determine the anti-...

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Bibliographic Details

Published in:	Pathogens
Main Authors:	Eric G. Romanowski, Kathleen A. Yates, Eric J. Daniels, Brian M. Strem, John E. Romanowski, Regis P. Kowalski
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Subjects:	ranpirnase RNase antiviral eye adenovirus EKC
Online Access:	https://www.mdpi.com/2076-0817/11/12/1485