Low doses of 3-phenyl-lawsone or meglumine antimoniate delivery by tattooing route are successful in reducing parasite load in cutaneous lesions of Leishmania (Viannia) braziliensis-infected hamsters

Current therapeutic ways adopted for the treatment of leishmaniasis are toxic and expensive including parasite resistance is a growing problem. Given this scenario, it is urgent to explore treatment alternatives for leishmaniasis. The aim of this study was to evaluate the effect of 3-phenyl-lawsone...

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Bibliographic Details

Published in:	Frontiers in Cellular and Infection Microbiology
Main Authors:	Rafaella de Miranda Villarim Meira, Sara Lins da Silva Gomes, Edgar Schaeffer, Thayssa Da Silva, Andréia Carolinne de Souza Brito, Larissa Moreira Siqueira, Job Domingos Inácio, Elmo Eduardo Almeida-Amaral, Alda Maria Da-Cruz, Milla Bezerra-Paiva, Renata Heisler Neves, Luciana Silva Rodrigues, Patricia Maria Lourenço Dutra, Paulo Roberto Ribeiro Costa, Alcides José Monteiro da Silva, Silvia Amaral Gonçalves Da-Silva
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Subjects:	Leishmania (Viannia) braziliensis 3-phenyl-lawsone chemotherapy tattooing subcutaneous hamster-model
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2023.1025359/full