The Calcineurin-Binding, Activity-Dependent Splice Variant Dynamin1xb Is Highly Enriched in Synapses in Various Regions of the Central Nervous System

In the present study, we generated and characterized a splice site-specific monoclonal antibody that selectively detects the calcineurin-binding dynamin1 splice variant dynamin1xb. Calcineurin is a Ca2+-regulated phosphatase that enhances dynamin1 activity and is an important Ca2+-sensing mediator o...

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Bibliographic Details

Published in:	Frontiers in Molecular Neuroscience
Main Authors:	Marie-Lisa Eich, Ekta Dembla, Silke Wahl, Mayur Dembla, Karin Schwarz, Frank Schmitz
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-07-01
Subjects:	dynamin1xb splice variant synapse retina darkness-induced synaptic recruitment of dynamin1xb calcineurin
Online Access:	http://journal.frontiersin.org/article/10.3389/fnmol.2017.00230/full