A Single Subcutaneous Dose of BMD-1141 Stimulates Hair Regrowth Comparable to Daily, High-Dose Ruxolitinib in a Mouse Model of Alopecia Areata

Alopecia areata (AA) is an autoimmune disorder of hair loss resulting from a T-cell mediated attack on hair follicles. Three Janus kinase (JAK) inhibitors have been approved for the treatment of moderate-to-severe alopecia areata; however, safety concerns for immunosuppressive therapy have limited t...

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Bibliographic Details
Published in:Cells
Main Authors: Robert Gensure, Brett King, Stephen Sikkink, Andrei Mardaryev, Robyn Goforth
Format: Article
Language:English
Published: MDPI AG 2025-08-01
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Online Access:https://www.mdpi.com/2073-4409/14/16/1251