Epigenetic modifications in KDM lysine demethylases associate with survival of early-stage NSCLC

Abstract Background KDM lysine demethylase family members are related to lung cancer clinical outcomes and are potential biomarkers for chemotherapeutics. However, little is known about epigenetic alterations in KDM genes and their roles in lung cancer survival. Methods Tumor tissue samples of 1230...

Full description

Bibliographic Details
Published in:Clinical Epigenetics
Main Authors: Yongyue Wei, Junya Liang, Ruyang Zhang, Yichen Guo, Sipeng Shen, Li Su, Xihong Lin, Sebastian Moran, Åslaug Helland, Maria M. Bjaanæs, Anna Karlsson, Maria Planck, Manel Esteller, Thomas Fleischer, Johan Staaf, Yang Zhao, Feng Chen, David C. Christiani
Format: Article
Language:English
Published: BMC 2018-04-01
Subjects:
KDM
Lysine demethylase
DNA methylation
Lung cancer
Survival
Online Access:http://link.springer.com/article/10.1186/s13148-018-0474-3

Internet

http://link.springer.com/article/10.1186/s13148-018-0474-3

Similar Items