β-1,3-Glucan-induced host phospholipase D activation is involved in Aspergillus fumigatus internalization into type II human pneumocyte A549 cells.

The internalization of Aspergillus fumigatus into lung epithelial cells is a process that depends on host cell actin dynamics. The host membrane phosphatidylcholine cleavage driven by phospholipase D (PLD) is closely related to cellular actin dynamics. However, little is known about the impact of PL...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Xuelin Han, Rentao Yu, Dongyu Zhen, Sha Tao, Martina Schmidt, Li Han
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Online Access:http://europepmc.org/articles/PMC3132740?pdf=render