Distinct immunity protein families mediate compartment-specific neutralization of a bacterial toxin

Summary: Staphylococcus aureus utilizes a type VII secretion system (T7SS) to secrete antibacterial toxins targeting competitor bacteria. EsxX is a T7SS substrate protein harboring an N-terminal LXG domain, which is secreted by ST398 strains. We demonstrate that the EsxX C terminus is a membrane-dep...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Felicity Alcock, Yaping Yang, Justin Deme, Guillermina Casabona, Chriselle Mendonca, Fatima Ulhuq, Susan Lea, Tracy Palmer
Format:	Article
Language:	English
Published:	Elsevier 2025-11-01
Subjects:	CP: Microbiology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124725012306