Rationally optimized generation of integrated Escherichia coli with stable and high yield lycopene biosynthesis from heterologous mevalonate (MVA) and lycopene expression pathways

The stability and high productivity of heterogeneous terpenoid production in Escherichia coli expression system is one of the most key issues for its large scale industrialization. In the current study on taking lycopene biosynthesis as an example, an integrated Escherichia coli system has been gene...

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Bibliographic Details

Published in:	Synthetic and Systems Biotechnology
Main Authors:	Muhammad Hammad Hussain, Qi Hong, Waqas Qamar Zaman, Ali Mohsin, Yanlong Wei, Ning Zhang, Hongqing Fang, Zejian Wang, Haifeng Hang, Yingping Zhuang, Meijin Guo
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2021-06-01
Subjects:	Escherichia coli Lycopene biosynthesis Rational model of expression pathways Integrated MVA pathway Fermentation
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405805X2100020X