Systematic review and feasibility study on pre-analytical factors and genomic analyses on archival formalin-fixed paraffin-embedded breast cancer tissue

Abstract Formalin-fixed paraffin-embedded (FFPE) tissue represents a valuable source for translational cancer research. However, the widespread application of various downstream methods remains challenging. Here, we aimed to assess the feasibility of a genomic and gene expression analysis workflow u...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Dimitrios Salgkamis, Emmanouil G. Sifakis, Susanne Agartz, Valtteri Wirta, Johan Hartman, Jonas Bergh, Theodoros Foukakis, Alexios Matikas, Ioannis Zerdes
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-08-01
Subjects:	Formalin-fixed Paraffin-embedded Preanalytical factors Next-generation sequencing Gene expression Breast cancer
Online Access:	https://doi.org/10.1038/s41598-024-69285-8