Wilforlide A ameliorates the progression of rheumatoid arthritis by inhibiting M1 macrophage polarization

Rheumatoid arthritis (RA) is an autoimmune disease with increased M1 macrophages. The classical activated M1 macrophages produce various cytokines to control inflammation. Wilforlide A is a natural product that displays anti-inflammatory activities. However, the effect of Wilforlide A on RA progress...

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Bibliographic Details

Published in:	Journal of Pharmacological Sciences
Main Authors:	Yunxiang Cao, Jian Liu, Chuanbing Huang, Yanhong Tao, Yuan Wang, Xi Chen, Dan Huang
Format:	Article
Language:	English
Published:	Elsevier 2022-01-01
Subjects:	Wilforlide A Rheumatoid arthritis Macrophage polarization TLR4 NF-κB
Online Access:	http://www.sciencedirect.com/science/article/pii/S1347861321001006