Subcortical and Deep Cortical Atrophy in Frontotemporal Dementia due to Granulin Mutations

Background/Aims: Parkinsonism is often associated with symptoms of frontotemporal dementia (FTD), but its pathogenesis has been largely neglected. In genetic inherited FTD-related granulin (GRN) mutations, parkinsonism is an early sign, and it is more common than in sporadic disorders. Our aim was t...

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Bibliographic Details
Published in:Dementia and Geriatric Cognitive Disorders Extra
Main Authors: Enrico Premi, Valentina Garibotto, Stefano Gazzina, Anna Formenti, Silvana Archetti, Roberto Gasparotti, Alessandro Padovani, Barbara Borroni
Format: Article
Language:English
Published: Karger Publishers 2014-04-01
Subjects:
Granulin
Magnetic resonance imaging
Subcortical regions
Basal ganglia
Frontotemporal dementia
Probabilistic atlases
Voxel-based morphometry
Online Access:http://www.karger.com/Article/FullText/355428

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http://www.karger.com/Article/FullText/355428

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