ER Stress Regulates Immunosuppressive Function of Myeloid Derived Suppressor Cells in Leprosy that Can Be Overcome in the Presence of IFN-γ

Summary: Myeloid derived suppressor cells (MDSCs) are a population of immature myeloid cells that suppress adaptive immune function, yet the factors that regulate their suppressive function in patients with infection remain unclear. We studied MDSCs in patients with leprosy, a disease caused by Myco...

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Bibliographic Details

Published in:	iScience
Main Authors:	Kindra M. Kelly-Scumpia, Aaron Choi, Roksana Shirazi, Hannah Bersabe, Esther Park, Philip O. Scumpia, Maria T. Ochoa, Jing Yu, Feiyang Ma, Matteo Pellegrini, Robert L. Modlin
Format:	Article
Language:	English
Published:	Elsevier 2020-05-01
Subjects:	Biological Sciences Immunology Immune Response Cell Biology Functional Aspects of Cell Biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004220302352