Population Pharmacokinetics of Hydroxychloroquine and 3 Metabolites in COVID-19 Patients and Pharmacokinetic/Pharmacodynamic Application

We develop a population pharmacokinetic model for hydroxychloroquine (HCQ) and three of its metabolites (desethylhydroxychloroquine, Des HCQ; desethylchloroquine, DesCQ; and didesethylchloroquine, didesCQ) in COVID-19 patients in order to determine whether a pharmacokinetic (PK)/pharmacodynamic (PD)...

詳細記述

書誌詳細

出版年:	Pharmaceuticals
主要な著者:	Jean Claude Alvarez, Benjamin Davido, Pierre Moine, Isabelle Etting, Djillali Annane, Islam Amine Larabi, Nicolas Simon
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2022-02-01
主題:	hydroxychloroquine desethylhydroxychloroquine desethylchloroquine didesethylchloroquine PK/PD COVID-19
オンライン･アクセス:	https://www.mdpi.com/1424-8247/15/2/256