Curcumin Decreases Viability and Inhibits Proliferation of Imatinib-Sensitive and Imatinib-Resistant Chronic Myeloid Leukemia Cell Lines

Chronic myeloid leukemia (CML) is a myeloproliferative haematological malignancy characterized by constitutive activation of BCR-ABL1 tyrosine kinase in the majority of patients. BCR-ABL1 expression activates signaling pathways involved in cell proliferation and survival. Current treatment options f...

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Bibliographic Details

Published in:	Metabolites
Main Authors:	Esma Bilajac, Lejla Mahmutović, Una Glamočlija, Amar Osmanović, Altijana Hromić-Jahjefendić, Murtaza M. Tambuwala, Mirza Suljagić
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Subjects:	curcumin chronic myeloid leukemia imatinib imatinib resistance
Online Access:	https://www.mdpi.com/2218-1989/13/1/58