Disruption in glutathione metabolism and altered energy production in the liver and kidney after ischemic acute kidney injury in mice

Abstract Acute kidney injury (AKI) is a systemic disease that affects energy metabolism in various remote organs in murine models of ischemic AKI. However, AKI-mediated effects in the liver have not been comprehensively assessed. After inducing ischemic AKI in 8–10-week-old, male C57BL/6 mice, mass...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Peter R. Baker, Amy S. Li, Benjamin R. Griffin, Hyo-Wook Gil, David J. Orlicky, Benjamin M. Fox, Bryan Park, Genevieve C. Sparagna, Jared Goff, Christopher Altmann, Hanan Elajaili, Kayo Okamura, Zhibin He, Daniel Stephenson, Angelo D’Alessandro, Julie A. Reisz, Eva S. Nozik, Carmen C. Sucharov, Sarah Faubel
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-06-01
Online Access:	https://doi.org/10.1038/s41598-024-64586-4