Nasal immunization with Streptococcus mutans membrane vesicles and eggshell-derived hydroxyapatites elicits enhanced antigen-specific mucosal IgA responses

Abstract Nasal vaccines characterized by secretory IgA (SIgA) induction are effective in preventing mucosal infection. SIgA induction is potentiated by mucosal adjuvants, and the exploration of new safe and effective candidates is important. Nanosized hydroxyapatites (HAs) have the potential to enha...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Scientific Reports
المؤلفون الرئيسيون:	Tomomi Hashizume-Takizawa, Chihiro Mochizuki, Yuki Sakai, Koichi Nakamura, Hirotaka Kobayashi, Hidenobu Senpuku
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Nature Portfolio 2025-10-01
الموضوعات:	Nasal immunization Mucosal adjuvant Eggshell Hydroxyapatites Membrane vesicle Glucosyltransferases
الوصول للمادة أونلاين:	https://doi.org/10.1038/s41598-025-19334-7

مواد مشابهة

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