Performance of αSynuclein RT-QuIC in relation to neuropathological staging of Lewy body disease

Abstract Currently, there is a need for diagnostic markers in Lewy body disorders (LBD). α-synuclein (αSyn) RT-QuIC has emerged as a promising assay to detect misfolded αSyn in clinically or neuropathologically established patients with various synucleinopathies. In this study, αSyn RT-QuIC was used...

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書誌詳細

出版年:	Acta Neuropathologica Communications
主要な著者:	Sara Hall, Christina D. Orrù, Geidy E. Serrano, Douglas Galasko, Andrew G. Hughson, Bradley R. Groveman, Charles H. Adler, Thomas G. Beach, Byron Caughey, Oskar Hansson
フォーマット:	論文
言語:	英語
出版事項:	BMC 2022-06-01
主題:	Cerebrospinal fluid Biomarkers Parkinson disease Dementia with Lewy bodies Lewy body dementia Diagnosis
オンライン･アクセス:	https://doi.org/10.1186/s40478-022-01388-7