Nephron‐Specific Disruption of Nitric Oxide Synthase 3 Causes Hypertension and Impaired Salt Excretion
Background In vitro studies suggest that nephron nitric oxide synthase 3 (NOS3) modulates tubule Na+ transport. Methods and Results To assess nephron NOS3 relevance in vivo, knockout (KO) mice with doxycycline‐inducible nephron‐wide deletion of NOS3 were generated. During 1 week of salt loading, KO...
| الحاوية / القاعدة: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
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| المؤلفون الرئيسيون: | , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
Wiley
2018-07-01
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://www.ahajournals.org/doi/10.1161/JAHA.118.009236 |
