Role of Innate Interferon Responses at the Ocular Surface in Herpes Simplex Virus-1-Induced Herpetic Stromal Keratitis

Herpes simplex virus type 1 (HSV-1) is a highly successful pathogen that primarily infects epithelial cells of the orofacial mucosa. After initial lytic replication, HSV-1 enters sensory neurons and undergoes lifelong latency in the trigeminal ganglion (TG). Reactivation from latency occurs througho...

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Bibliographic Details

Published in:	Pathogens
Main Authors:	Jiayi Ren, Ferrin Antony, Barry T. Rouse, Amol Suryawanshi
Format:	Article
Language:	English
Published:	MDPI AG 2023-03-01
Subjects:	HSV-1 HSK HSE IFN-α IFN-β IFN-λ
Online Access:	https://www.mdpi.com/2076-0817/12/3/437