Activator protein transcription factors coordinate human IL-33 expression from noncanonical promoters in chronic airway disease
IL-33 is a cytokine central to type 2 immune pathology in chronic airway disease. This cytokine is abundantly expressed in the respiratory epithelium and increased in disease, but how expression is regulated is undefined. Here we show that increased IL33 expression occurs from multiple noncanonical...
| الحاوية / القاعدة: | JCI Insight |
|---|---|
| المؤلفون الرئيسيون: | , , , , , , , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
American Society for Clinical investigation
2024-03-01
|
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1172/jci.insight.174786 |