The effect of chronic ozone exposure on the activation of endoplasmic reticulum stress and apoptosis in rat hippocampus

The chronic exposure to low doses of ozone, like in environmental pollution, leads to a state of oxidative stress, which has been proposed to contribute to neurodegenerative disorders, including Alzheimer's disease. It induces an increase of calcium in the endoplasmic reticulum (ER), which prod...

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Bibliographic Details

Published in:	Frontiers in Aging Neuroscience
Main Authors:	Erika Rodríguez-Martínez, Concepcion Nava-Ruiz, Elsa Escamilla-Chimal, Gabino Borgonio-Perez, Selva Rivas - Arancibia
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-10-01
Subjects:	Apoptosis Endoplasmic Reticulum Stress Hippocampus Oxidative Stress Ozone
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnagi.2016.00245/full