Sub-acute Toxicity Assessment of Taxol Isolated From Fusarium Solani, an Endophytic Fungus of Taxus Brevifolia, in Wistar Rats and Analyzing Its Cytotoxicity and Apoptotic Potential in Lung Cancer Cells

The limited availability of taxol from plant sources has prompted the scientific world to look for an alternative, as in the chemical synthesis of tissue cultures of the Taxus species, to meet the increasing demand for the drug. However, these alternative means are expensive or result in low yield....

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Gini C. Kuriakose, B. P. Arathi, Mangalath Divya Lakshmanan, M. V. Jiby, Ramachandra Subbaraya Gudde, C. Jayabhaskaran
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-10-01
Subjects:	taxol sub-acute toxicity cell cycle arrest mitochondria membrane potential loss apoptosis F. solani
Online Access:	https://www.frontiersin.org/article/10.3389/fonc.2020.538865/full