Efficacy and safety evaluation of artificial intelligence-identified antimicrobial peptides targeting avian pathogenic Escherichia coli in broiler chickens

Abstract Background The overuse of antibiotics in both veterinary and human medicine has resulted in the emergence of antibiotic-resistant bacteria, prompting a search for effective alternatives. Antimicrobial peptides (AMPs) are short, often cationic, peptide-based molecules with antimicrobial and...

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Bibliographic Details

Published in:	Journal of Animal Science and Biotechnology
Main Authors:	Emre Demirsoy, Teagan I. Parkin, Shaeleen E. Mihalynuk, Anna H. Dema, Lorissa Corrie, Marika E. Heilker, Haley N. Kuecks-Winger, Anat Yanai, Uluc B. Birol, Michael McIlwee, Kay de Wet, Mathijs Knipscheer, Victoria Bowes, Vanessa Tuytel, Liam Ritchie, Wolfgang Köster, Emil Berberov, William R. Cox, Monica Kotkoff, Vanessa C. Thompson, René L. Warren, Erin Fraser, Linda M. N. Hoang, Fraser Hof, Fatih Birol, Caren C. Helbing, Inanc Birol
Format:	Article
Language:	English
Published:	BMC 2026-05-01
Subjects:	Antimicrobial peptide APEC Broiler chicken Efficacy Immunomodulation Safety
Online Access:	https://doi.org/10.1186/s40104-026-01417-8