Long-term analysis of humoral responses and spike-specific T cell memory to Omicron variants after different COVID-19 vaccine regimens

BackgroundThe emergence of SARS-CoV-2 variants has raised concerns about the sustainability of vaccine-induced immunity. Little is known about the long-term humoral responses and spike-specific T cell memory to Omicron variants, with specific attention to BA.4/5, BQ.1.1, and XBB.1.MethodsWe assessed...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Chia-Lo Ho, Li-Chen Yen, Hong-Wei Huang, Chun-Chi Lu, Yi-Jen Hung, Ching-Len Liao, Chin-Mao Hung, Kuo-Chou Chiu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-03-01
Subjects:	SARS-CoV-2 Omicron variant vaccination neutralizing antibody cellular immune response
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1340645/full