Impaired cardiac pumping function and increased afterload as determinants of early hemodynamic alterations in Cushing disease

Abstract The long-term hypercortisolemia of Cushing disease (CD) may lead to hemodynamic disorders by increasing subclinical cardiac and vascular dysfunction. The purpose of this observational cohort study was to assess the relationship between hemodynamic parameters evaluated via impedance cardiogr...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Agnieszka Włochacz, Paweł Krzesiński, Beata Uziębło-Życzkowska, Przemysław Witek, Grzegorz Zieliński, Anna Kazimierczak, Robert Wierzbowski, Małgorzata Banak, Grzegorz Gielerak
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-01-01
Subjects:	Cushing disease Echocardiography Global longitudinal strain Hemodynamic disorders Impedance cardiography Pituitary neuroendocrine tumor
Online Access:	https://doi.org/10.1038/s41598-024-84888-x