ZO-1 Guides Tight Junction Assembly and Epithelial Morphogenesis via Cytoskeletal Tension-Dependent and -Independent Functions

Formation and maintenance of tissue barriers require the coordination of cell mechanics and cell–cell junction assembly. Here, we combined methods to modulate ECM stiffness and to measure mechanical forces on adhesion complexes to investigate how tight junctions regulate cell mechanics and epithelia...

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Bibliographic Details

Published in:	Cells
Main Authors:	Alexis J. Haas, Ceniz Zihni, Susanne M. Krug, Riccardo Maraspini, Tetsuhisa Otani, Mikio Furuse, Alf Honigmann, Maria S. Balda, Karl Matter
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Subjects:	tight junction myosin F-actin stiffness ECM tension
Online Access:	https://www.mdpi.com/2073-4409/11/23/3775