TORREY, a Phase 2 study to evaluate the efficacy and safety of inhaled seralutinib for the treatment of pulmonary arterial hypertension

Aberrant kinase signaling that involves platelet‐derived growth factor receptor (PDGFR) α/β, colony stimulating factor 1 receptor (CSF1R), and stem cell factor receptor (c‐KIT) pathways may be responsible for vascular remodeling in pulmonary arterial hypertension. Targeting these specific pathways m...

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Bibliographic Details

Published in:	Pulmonary Circulation
Main Authors:	Robert P. Frantz, Raymond L. Benza, Richard N. Channick, Kelly Chin, Luke S. Howard, Vallerie V. McLaughlin, Olivier Sitbon, Roham T. Zamanian, Anna R. Hemnes, Matt Cravets, Jean‐Marie Bruey, Robert Roscigno, David Mottola, Erin Elman, Lawrence S. Zisman, Hossein‐Ardeschir Ghofrani
Format:	Article
Language:	English
Published:	Wiley 2021-10-01
Subjects:	pulmonary vascular remodeling PDGFR CSF1R c‐KIT BMPR2 GB002
Online Access:	https://doi.org/10.1177/20458940211057071