The overexpression of genes of thiol metabolism contribute to drug resistance in clinical isolates of visceral leishmaniasis (kala azar) in India

Abstract Background Visceral leishmaniasis (VL), also called Kala Azar (KA) or black fever in India, claims around 20,000 lives every year. Chemotherapy remains one of the most important tools in the control of VL. Current chemotherapy for Kala Azar in India relies on a rather limited arsenal of dru...

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Bibliographic Details
Published in:Parasites & Vectors
Main Authors: Neeloo Singh, Mitali Chatterjee, Shyam Sundar
Format: Article
Language:English
Published: BMC 2014-12-01
Subjects:
Leishmania donovani
Drug resistance
Drug efflux
Thiols
Clinical isolates
Online Access:https://doi.org/10.1186/s13071-014-0596-1

Internet

https://doi.org/10.1186/s13071-014-0596-1

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