Advanced image-free analysis of the nano-organization of chromatin and other biomolecules by Single Molecule Localization Microscopy (SMLM)

The cell as a system of many components, governed by the laws of physics and chemistry drives molecular functions having an impact on the spatial organization of these systems and vice versa. Since the relationship between structure and function is an almost universal rule not only in biology, appro...

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Bibliographic Details

Published in:	Computational and Structural Biotechnology Journal
Main Authors:	Jonas Weidner, Charlotte Neitzel, Martin Gote, Jeanette Deck, Kim Küntzelmann, Götz Pilarczyk, Martin Falk, Michael Hausmann
Format:	Article
Language:	English
Published:	Elsevier 2023-01-01
Subjects:	Single molecule localization microscopy (SMLM) Ripley distance frequency histograms Persistent homology Persistent image Principal component analysis Application of mathematical analysis tools to chromatin organization and DNA repair processes
Online Access:	http://www.sciencedirect.com/science/article/pii/S2001037023001083