Antimicrobial activity, membrane interaction and structural features of short arginine-rich antimicrobial peptides

Antimicrobial activity of many AMPs can be improved by lysine-to-arginine substitution due to a more favourable interaction of arginine guanidinium moiety with bacterial membranes. In a previous work, the structural and functional characterization of an amphipathic antimicrobial peptide named RiLK1,...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Bruna Agrillo, Alessandra Porritiello, Lorena Gratino, Marco Balestrieri, Yolande Therese Proroga, Andrea Mancusi, Loredana Cozzi, Teresa Vicenza, Principia Dardano, Bruno Miranda, Pablo V. Escribá, Marta Gogliettino, Gianna Palmieri
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-10-01
Subjects:	antimicrobial compound cationic arginine-rich peptide arginine membrane interaction spectroscopy
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1244325/full