Role of FOXO3 Activated by HIV-1 Tat in HIV-Associated Neurocognitive Disorder Neuronal Apoptosis

There are numerous types of pathological changes in human immunodeficiency virus (HIV)-associated neurocognitive disorder (HAND), including apoptosis of neurons. HIV-1 transactivator of transcription (Tat) protein, which is encoded by HIV-1, may promote apoptosis in HAND. Forkhead box O3 (FOXO3) is...

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Bibliographic Details
Published in:	Frontiers in Neuroscience
Main Authors:	Huaqian Dong, Xiang Ye, Li Zhong, Jinhong Xu, Jinhua Qiu, Jun Wang, Yiming Shao, Huiqin Xing
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-02-01
Subjects:	FOXO3 apoptosis HIV-1 Tat HIV-associated neurocognitive disorder JNK
Online Access:	https://www.frontiersin.org/article/10.3389/fnins.2019.00044/full

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