Impaired hydrogen sulfide biosynthesis underlies eccentric contraction–induced force loss in dystrophin-deficient skeletal muscle

Eccentric contraction–induced (ECC-induced) force loss is a hallmark of murine dystrophin-deficient (mdx) skeletal muscle that is used to assess efficacy of potential therapies for Duchenne muscular dystrophy. While virtually all key proteins involved in muscle contraction have been implicated in EC...

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Bibliographic Details

Published in:	The Journal of Clinical Investigation
Main Authors:	W. Michael Southern, Erynn E. Johnson, Elizabeth K. Fasbender, Katherine S. Fallon, Courtney L. Cavazos, Dawn A. Lowe, George G. Rodney, James M. Ervasti
Format:	Article
Language:	English
Published:	American Society for Clinical Investigation 2025-03-01
Subjects:	Metabolism Muscle biology
Online Access:	https://doi.org/10.1172/JCI176942