Association of Sonic Hedgehog with the extracellular matrix requires its zinc-coordination center

Abstract Background Sonic Hedgehog (Shh) has a catalytic cleft characteristic for zinc metallopeptidases and has significant sequence similarities with some bacterial peptidoglycan metallopeptidases defining a subgroup within the M15A family that, besides having the characteristic zinc coordination...

詳細記述

書誌詳細
出版年:BMC Molecular and Cell Biology
主要な著者: Carina Jägers, Henk Roelink
フォーマット: 論文
言語:英語
出版事項: BMC 2021-04-01
主題:
オンライン・アクセス:https://doi.org/10.1186/s12860-021-00359-5