Association of Sonic Hedgehog with the extracellular matrix requires its zinc-coordination center
Abstract Background Sonic Hedgehog (Shh) has a catalytic cleft characteristic for zinc metallopeptidases and has significant sequence similarities with some bacterial peptidoglycan metallopeptidases defining a subgroup within the M15A family that, besides having the characteristic zinc coordination...
| 發表在: | BMC Molecular and Cell Biology |
|---|---|
| Main Authors: | Carina Jägers, Henk Roelink |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
BMC
2021-04-01
|
| 主題: | |
| 在線閱讀: | https://doi.org/10.1186/s12860-021-00359-5 |
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