Type II Collagen-Specific B Cells Induce Immune Tolerance in Th1-Skewed, Th2-Skewed, and Arthritis-Prone Strains of Mice

Antigen-specific regulatory T cells play key immune suppressive roles in autoimmune disease models and regulate the peripheral tolerance achieved via anterior chamber-associated immune deviation (ACAID). Articular cartilage has type II collagen (CII), which is a potent autoantigen protein in arthrit...

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發表在:	Cells
Main Authors:	Shukkur M. Farooq, Hossam M. Ashour
格式:	Article
語言:	英语
出版:	MDPI AG 2021-04-01
主題:	ACAID peripheral tolerance immune privilege regulatory T cells collagen type II B cells
在線閱讀:	https://www.mdpi.com/2073-4409/10/4/870