SARS-CoV-2-specific circulating T follicular helper cells correlate with neutralizing antibodies and increase during early convalescence.

T-cell immunity is likely to play a role in protection against SARS-CoV-2 by helping generate neutralizing antibodies. We longitudinally studied CD4 T-cell responses to the M, N, and S structural proteins of SARS-CoV-2 in 26 convalescent individuals. Within the first two months following symptom ons...

Full description

Bibliographic Details

Published in:	PLoS Pathogens
Main Authors:	Sushma Boppana, Kai Qin, Jacob K Files, Ronnie M Russell, Regina Stoltz, Frederic Bibollet-Ruche, Anju Bansal, Nathan Erdmann, Beatrice H Hahn, Paul A Goepfert
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2021-07-01
Online Access:	https://doi.org/10.1371/journal.ppat.1009761