Efficacy of Modified Upadacitinib Dosing in Pediatric Refractory IBD: A Case-Based Analysis

This case report describes four pediatric patients with severe, therapy-refractory ulcerative colitis (UC) and one pediatric patient with severe, therapy-refractory Crohn’s disease (CD), all of whom failed widely used biologic therapies, including the approved treatments infliximab and adalimumab, a...

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Bibliographic Details

Published in:	Children
Main Authors:	Frank Risto Rommel, Christa Bergheim, Inga Jerrentrup, Stefanie Weber, Andreas Jenke
Format:	Article
Language:	English
Published:	MDPI AG 2025-09-01
Subjects:	VEO-IBD IBD children upadacitinib JAK inhibitor rescue therapy
Online Access:	https://www.mdpi.com/2227-9067/12/9/1268