HMGB1-mediated macrophage polarization to M2 phenotype promotes ureteral stricture: therapeutic potential of HMGB1 inhibitors

Abstract Background Ureteral stricture is a common condition characterized by fibrotic narrowing of the ureter, often resulting in obstruction and impaired renal function. The condition is typically associated with chronic inflammation, epithelial injury, and abnormal wound healing responses, leadin...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	European Journal of Medical Research
المؤلفون الرئيسيون:	Jie Zheng, Lingsong Tao, Yingqing Liu, Yang Zhang, Li Cheng, Zongyao Hao
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	BMC 2025-09-01
الموضوعات:	HMGB1 Ureteral stricture Macrophage polarization TGF-β Fibroblast activation Glycyrrhizin
الوصول للمادة أونلاين:	https://doi.org/10.1186/s40001-025-03137-7

مواد مشابهة

Disulfide and Fully Reduced HMGB1 Induce Different Macrophage Polarization and Migration Patterns
حسب: Henna Salo, وآخرون
منشور في: (2021-05-01)

Macrophage-derived exosomal HMGB3 regulates silica-induced pulmonary inflammation by promoting M1 macrophage polarization and recruitment
حسب: Xiaofeng Qin, وآخرون
منشور في: (2024-03-01)

Glycyrrhizin, an inhibitor of HMGB1 induces autolysosomal degradation function and inhibits Helicobacter pylori infection
حسب: Uzma Khan, وآخرون
منشور في: (2023-04-01)

HMGB1 Modulates Macrophage Metabolism and Polarization in Ulcerative Colitis by Inhibiting Cpt1a Expression
حسب: Fenfen Wang, وآخرون
منشور في: (2024-11-01)

Transcriptomic Profiling Reveals That HMGB1 Induces Macrophage Polarization Different from Classical M1
حسب: Heshuang Qu, وآخرون
منشور في: (2022-06-01)

Changing trends in the management of posttransplant ureteric stricture
حسب: Sunirmal Choudhury, وآخرون
منشور في: (2024-01-01)

Laparoscopic and Robot-Assisted Laparoscopic Management of Iatrogenic Ureteral Strictures: Preliminary Experience
حسب: Roxana Andra Coman, وآخرون
منشور في: (2025-04-01)

Inhibition of Ureteral Stricture by Pirfenidone-Loaded Nanoparticle-Coated Ureteral Stents with Slow-Release Pirfenidone
حسب: Jiang Z, وآخرون
منشور في: (2022-12-01)

Thermoexpandable Memokath stent: Usage and efficacy in ureteral and urethral strictures in Saudi Arabia
حسب: Omar Buksh, وآخرون
منشور في: (2024-01-01)

HMGB1 Inhibition Alleviates Chronic Nonbacterial Prostatitis by Suppressing M1 Polarization of Macrophages
حسب: Zhou J, وآخرون
منشور في: (2025-05-01)

HMGB1 mediates lipopolysaccharide-induced macrophage autophagy and pyroptosis
حسب: Jiawei Shang, وآخرون
منشور في: (2023-01-01)

Treatment algorithm for robotic transplant ureteral stricture repair
حسب: Emily Ji, وآخرون
منشور في: (2025-03-01)

LONG URETERIC STRICTURES MANAGED BY USING BUCCAL MUCOSAL GRAFTS
حسب: Rajendra Nerli, وآخرون
منشور في: (2023-09-01)

A New Self-expanding, Large-caliber Ureteral Stent Applied for Bilateral Long-segment Ureteral Strictures — A Case Report
حسب: Hsuan-Yun Hsu, وآخرون
منشور في: (2024-10-01)

Glycyrrhizin alleviates contrast-induced acute kidney injury via inhibiting HMGB1-mediated renal tubular epithelial cells ferroptosis
حسب: Fang-yuan Tian, وآخرون
منشور في: (2025-12-01)

Ureteral Stricture Outcomes Using Small Ureteral Access Sheath During Retrograde Intrarenal Surgery
حسب: Özer Güzel, وآخرون
منشور في: (2023-12-01)

Glycyrrhizin ameliorates colorectal cancer progression by regulating NHEJ pathway through inhibiting HMGB1-induced DNA damage response
حسب: Yuhui Han, وآخرون
منشور في: (2024-10-01)

BUCCAL MUCOSAL GRAFT ONLAY TECHNIQUE FOR UPPER URETERIC AND UPJ STRICTURES
حسب: Rajendra Nerli, وآخرون
منشور في: (2024-01-01)

IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development
حسب: Lei Lv, وآخرون
منشور في: (2024-03-01)

The efficacy and safety of ureteral dilation and long-term type ureteral stent for patients with ureteral obstruction
حسب: Ming-Hong Kao, وآخرون
منشور في: (2015-03-01)

Can preoperative ureteral stents reduce the incidence of ureteral stricture after radiotherapy in patients with cervical cancer?
حسب: Liang Liu, وآخرون
منشور في: (2022-07-01)

Long-term Outcomes of Minimally Invasive Rendezvous Procedures to Treat Complex Ureteric Strictures and Injuries
حسب: Giorgio Mazzon, وآخرون
منشور في: (2023-03-01)

Ureteral stricture formation after removal of proximal ureteral stone: retroperitoneal laparoscopic ureterolithotomy versus ureteroscopy with holmium: YAG laser lithotripsy
حسب: Henglong Hu, وآخرون
منشور في: (2017-06-01)

Laparoscopic ureteroneocystostomy for mid and lower ureteric strictures: Experience from a tertiary center
حسب: Manmeet Singh, وآخرون
منشور في: (2018-01-01)

NRF3 suppresses the malignant progression of TNBC by promoting M1 polarization of macrophages via ROS/HMGB1 axis
حسب: Ping Xing, وآخرون
منشور في: (2024-12-01)

A case report on buccal mucosa graft for upper ureteral stricture repair
حسب: Vilas Pandurang Sabale, وآخرون
منشور في: (2016-01-01)

Minimally invasive robotic ureteral reconstruction using endoscopic submucosal dissection harvested colorectal mucosa graft for ureteral stricture
حسب: Haihang Nie, وآخرون
منشور في: (2025-04-01)

Preliminary Outcomes of Different Tactics of Ureteral Stent Placement in Patients with Ureteral Stricture Undergoing Balloon Dilatation: Experience from a Large-Scale Center
حسب: Xiao Hu, وآخرون
منشور في: (2022-05-01)

Robotic ureteral reconstruction for benign ureteral strictures: a systematic review of surgical techniques, complications and outcomes
حسب: Kunlin Yang, وآخرون
منشور في: (2023-10-01)

Robot-assisted appendiceal interposition for long segment ureteric stricture: A case report
حسب: G.S. Bora, وآخرون
منشور في: (2025-09-01)

Congenital mid-ureteral stricture: a case report of two patients
حسب: Hamdan Alhazmi, وآخرون
منشور في: (2018-11-01)

Extended Boari-flap reconstruction in isolated tuberculous pan-ureteral stricture
حسب: Shanmugasundaram Rajaian, وآخرون
منشور في: (2020-01-01)

Therapeutic administration of etoposide coincides with reduced systemic HMGB1 levels in macrophage activation syndrome
حسب: Karin Palmblad, وآخرون
منشور في: (2021-05-01)

Successful use of ovarian vein as a ureteral substitute for long-segment ureteral stricture post-pelvic radiotherapy: a case report
حسب: Wenqiang Cai, وآخرون
منشور في: (2025-10-01)

Robotic ureteral reconstruction for recurrent strictures after prior failed management
حسب: Matthew Lee, وآخرون
منشور في: (2023-05-01)

Management of recurrent ureteral stricture: a retrospectively comparative study with robot-assisted laparoscopic surgery versus open approach
حسب: Qing Wang, وآخرون
منشور في: (2019-12-01)

MFG-E8 and HMGB1 Are Involved in the Mechanism Underlying Alcohol-Induced Impairment of Macrophage Efferocytosis
حسب: Xiao Wang, وآخرون
منشور في: (2013-03-01)

SARS-CoV-2 ORF3a induces COVID-19-associated kidney injury through HMGB1-mediated cytokine production
حسب: Chenyu Zhang, وآخرون
منشور في: (2024-11-01)

Use of mitrofanoff and Yang-Monti techniques as ureteric substitution for severe schistosomal bilateral ureteric stricture: A case report and review of the literature
حسب: Abubakar Alhaji Bakari, وآخرون
منشور في: (2012-01-01)

LAPAROSCOPIC TRANSPERITONEAL URETEROURETEROSTOMY COMBINED WITH RETROGRADE FLEXIBLE URETEROSCOPY ASSISTANCE FOR URETERAL STRICTURE- CASE SERIES OF SEVEN PATIENTS
حسب: Deyan Anakievski
منشور في: (2021-09-01)