Immediate versus gradual TocilizuMab discontinuAtion in GIant Cell Arteritis: protocol of the multicentre randomised open-label MAGICA trial

Introduction Giant cell arteritis (GCA) is a large-vessel vasculitis occurring in people aged over 50 years. Recent studies have shown that tocilizumab (TCZ), an anti-IL-6 receptor monoclonal antibody, is remarkably effective in treating GCA and allows significant dose sparing of glucocorticoids. Ho...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:BMJ Open
المؤلفون الرئيسيون: Hervé Devilliers, Maxime Samson, Bernard Bonnotte, Isabelle Fournel, Abderrahmane Bourredjem, Claudie Cladière, Maud Carpentier, Camille Fleck, Amelie Cransac, Marion Cortier, Emilie Galizzi, Marion Brayer, Jean-Louis Alberini
التنسيق: مقال
اللغة:الإنجليزية
منشور في: BMJ Publishing Group 2025-10-01
الوصول للمادة أونلاين:https://bmjopen.bmj.com/content/15/10/e108115.full