Disruption of LRRK2 does not cause specific loss of dopaminergic neurons in zebrafish.
Mutations in LRRK2 are genetically linked to Parkinson's disease (PD) but its normal biological function is largely unknown. Sheng et al. recently reported that deletion of the WD40 domain of LRRK2 in zebrafish specifically causes PD-like loss of neurons and behavior defect. However, our simila...
| الحاوية / القاعدة: | PLoS ONE |
|---|---|
| المؤلفون الرئيسيون: | , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
Public Library of Science (PLoS)
2011-01-01
|
| الوصول للمادة أونلاين: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0020263&type=printable |