Relationships between Lipid-Related Metabolites and Age-Related Macular Degeneration Vary with Complement Genotype

Objective: Lipid dysregulation and complement system (CS) activation are 2 important pathophysiology pathways for age-related macular degeneration (AMD). We hypothesized that the relationship between lipids and AMD may also differ according to CS genotype profile. Thus, the objective was to investig...

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Bibliographic Details

Published in:	Ophthalmology Science
Main Authors:	Ralene Zi Hui Sim, MD, Yih-Chung Tham, PhD, Bjorn Kaijun Betzler, MBBS, Lei Zhou, PhD, Xiaomeng Wang, PhD, Charumathi Sabanayagam, MD, PhD, Gemmy Chiu Ming Cheung, MD, PhD, Tien Yin Wong, MD, PhD, Ching-Yu Cheng, MD, PhD, Simon Nusinovici, PhD
Format:	Article
Language:	English
Published:	Elsevier 2022-12-01
Subjects:	Age-related macular degeneration Complement system Lipids Metabolites
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666914522001002