cGAS-STING-TBK1 Signaling Promotes Valproic Acid-Responsive Human Cytomegalovirus Immediate-Early Transcription during Infection of Incompletely Differentiated Myeloid Cells

Repression of human cytomegalovirus (HCMV) immediate-early (IE) gene expression is a key regulatory step in the establishment and maintenance of latent reservoirs. Viral IE transcription and protein accumulation can be elevated during latency by treatment with histone deacetylase inhibitors such as...

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Bibliographic Details
Published in:Viruses
Main Authors: Emily R. Albright, Robert F. Kalejta
Format: Article
Language:English
Published: MDPI AG 2024-05-01
Subjects:
Online Access:https://www.mdpi.com/1999-4915/16/6/877