Genome-wide location analysis reveals distinct transcriptional circuitry by paralogous regulators Foxa1 and Foxa2.

Gene duplication is a powerful driver of evolution. Newly duplicated genes acquire new roles that are relevant to fitness, or they will be lost over time. A potential path to functional relevance is mutation of the coding sequence leading to the acquisition of novel biochemical properties, as analyz...

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Bibliographic Details

Published in:	PLoS Genetics
Main Authors:	Irina M Bochkis, Jonathan Schug, Diana Z Ye, Svitlana Kurinna, Sabrina A Stratton, Michelle C Barton, Klaus H Kaestner
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Online Access:	http://europepmc.org/articles/PMC3380847?pdf=render