Rescue of αB Crystallin (HSPB5) Mutants Associated Protein Aggregation by Co-Expression of HSPB5 Partners.

HSPB5 (also called αB-crystallin) is a ubiquitously expressed small heat shock protein. Mutations in HSPB5 have been found to cause cataract, but are also associated with a subgroup of myofibrillar myopathies. Cells expressing each of these HSPB5 mutants are characterized by the appearance of protei...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Rasha M Hussein, Ivor J Benjamin, Harm H Kampinga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Online Access:https://doi.org/10.1371/journal.pone.0126761