“Seeing Is Believing”: How Neutron Crystallography Informs Enzyme Mechanisms by Visualizing Unique Water Species

Hydrogen is the lightest atom and composes approximately half of the atomic content in macromolecules, yet their location can only be inferred or predicted in most macromolecular structures. This is because hydrogen can rarely be directly observed by the most common structure determination technique...

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Bibliographic Details

Published in:	Biology
Main Authors:	Qun Wan, Brad C. Bennett
Format:	Article
Language:	English
Published:	MDPI AG 2024-10-01
Subjects:	neutron diffraction deuterium hydronium protein structure enzyme catalysis H/D exchange
Online Access:	https://www.mdpi.com/2079-7737/13/11/850