Polyomavirus large T antigens: Unraveling a complex interactome

All members of the polyomavirus family encode a large T antigen (LT) protein that plays essential roles in viral DNA replication, regulation of viral gene expression, and the manipulation of numerous cellular pathways. Over 100 polyomaviruses have been discovered in hosts ranging from arthropods and...

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Bibliographic Details
Published in:Tumour Virus Research
Main Authors: Matthew R. Googins, Ping An, Christian H. Gauthier, James M. Pipas
Format: Article
Language:English
Published: Elsevier 2025-06-01
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666679024000302