Hypoxia-induced CTCF promotes EMT in breast cancer

Summary: Cancer cells experiencing hypoxic stress employ epithelial-mesenchymal transition (EMT) to undergo metastasis through rewiring of the chromatin landscape, epigenetics, and importantly, gene expression. Here, we showed that hypoxia modulates the epigenetic landscape on CTCF promoter and upre...

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Bibliographic Details
Published in:Cell Reports
Main Authors: Parik Kakani, Shruti Ganesh Dhamdhere, Deepak Pant, Rushikesh Joshi, Jharna Mishra, Atul Samaiya, Sanjeev Shukla
Format: Article
Language:English
Published: Elsevier 2024-07-01
Subjects:
CP: Cancer
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724006958

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http://www.sciencedirect.com/science/article/pii/S2211124724006958

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