RIPK3-deficient mice were not protected from nephrotoxic nephritis

Abstract Background Necrotizing glomerular lesions are a feature of severe glomerulonephritis. Unlike apoptosis, cellular necrosis has the potential to release damage-associated proteins into the microenvironment, thereby potentiating inflammation. Until recently necrosis was thought to be an unregu...

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Bibliographic Details
Published in:BMC Nephrology
Main Authors: N. R. Hill, H. T. Cook, C. D. Pusey, R. M. Tarzi
Format: Article
Language:English
Published: BMC 2018-03-01
Subjects:
Necroptosis
RIPK3
Glomerulonephritis
Nephrotoxic nephritis
Online Access:http://link.springer.com/article/10.1186/s12882-018-0850-4

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http://link.springer.com/article/10.1186/s12882-018-0850-4

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