Could brain-derived neurotrophic factor, irisin, and peroxisome proliferator-activated receptor-gamma be a pathway in cognitive impairment in schizophrenia?

Abstract Objective Previous research has indicated the brain-derived neurotrophic factor (BDNF) level is lower in schizophrenia and associated with cognitive impairment. Irisin-BDNF axis may strengthen learning and memory functions. This study examined associations between BDNF, peroxisome prolifera...

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Bibliographic Details
Published in:BMC Psychiatry
Main Authors: Hasan Ünver, Evrim Bayrak Oruc, Ezel Yıldırım, Semih Ergisi, Ali Yalçındağ, Aysegül Dağdeviren, Sibel Örsel, Gamze Erzin
Format: Article
Language:English
Published: BMC 2026-02-01
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Online Access:https://doi.org/10.1186/s12888-026-07913-5